PRP可用於預防掉髮
PRP可用於預防掉髮
研究使用12隻大鼠進行試驗。由其中的2隻大鼠提供捐血獲得PRP，另外10隻用於臨床和組織學分析。結果沒有使用 PRP 的區域：8 隻大鼠出現脫髮和 7隻大鼠發生局部色素減退，其中60% 出現完全脫髮，20% 出現部分脫髮，20% 未出現脫髮。有使用 PRP 的區域：4 隻出現脫髮和 3 隻色素減退，其中無完全脫髮病例，40%出現部分脫髮，60%未出現脫髮。從組織學分析中收集的數據顯示，有使用PRP 的那些區域中，100% 出現輕至中度萎縮；另一方面，沒有使用 PRP 的區域，80% 出現中至重度萎縮，20% 出現輕至中度萎縮。PRP 可用於預防脫髮。
PRP科技新知- PRP可用於預防掉髮
研究背景:
放射治療(放療)所造成的放射性皮膚炎會嚴重影響患者的生活品質，在某些情況下還會影響整形重建的癒合時間。富含血小板血漿（PRP）是一種新興療法。 PRP目前的用途包括：減緩局部發炎、促進傷口癒合、治療放療所引起的皮膚潰瘍，其用途延伸到美容整形外科領域，改善皮膚品質。
研究目的:
使用 PRP 作為放療後皮膚毛髮損傷的預防。
研究方式:
使用12 隻 Wistar 大鼠進行雙盲試驗。由其中的2隻大鼠提供捐血獲得PRP，另外10隻用於臨床和組織學分析。
結果:
在放療前沒有使用 PRP 的區域：8隻大鼠出現脫髮和7隻大鼠發生局部色素減退，其中60% 出現完全脫髮，20% 出現部分脫髮，20% 未出現脫髮。在放療前有使用 PRP 的區域：4 隻出現脫髮和 3 隻色素減退，其中無完全脫髮病例，40%出現部分脫髮，60%未出現脫髮。從組織學分析中收集的數據顯示，有使用PRP 的那些區域中，100% 出現輕至中度萎縮；另一方面，沒有使用 PRP 的區域，80% 出現中至重度萎縮，20% 出現輕至中度萎縮。
結論: PRP 可用於預防脫髮。
原文摘要:
Background and Objectives: Radiotherapy is usually associated with skin complications that affect the quality of life of patients and in some cases can also affect the timing of the reconstruction. The platelet rich plasma (PRP) is an emerging therapy; is autologous, safe and economic. Current use of PRP includes: efficacy in decreasing local inflammation, enhance wound healing, treatment of skin ulcers caused by radiotherapy and its use extends to the field of aesthetic plastic surgery improving the quality of the skin. The authors made an experimental trial to analyze the use of PRP as a prophylaxis method for skin damage after radiotherapy. We analyze the benefits of PRP as a prophylaxis method for skin damage after radiotherapy using an experimental model.
Methods: We conduct a double blind trial with rats. Twelve Wistar rats were used, 2 for obtaining the PRP and 10 for clinical and histological analysis.
Results: Data collected from the clinical analysis showed that those areas without PRP: 8 rats presented alopecia and 7 hypopigmentation. Total alopecia was present in 60%, partial alopecia in 20%, and 20% did not present alopecia. In those areas with PRP before radiotherapy: 4 presented alopecia and 3 hypopigmentation. There were no cases of total alopecia, 60% did not present alopecia and 40% presented partial alopecia. Data collected from the histological analysis showed 100% of mild-moderate atrophy in those areas with PRP. On the other hand, 80% of moderate-severe atrophy and 20% of mild-moderate atrophy was present on those areas without PRP.
Conclusions: The authors showed the benefit of PRP as a prophylaxis method for alopecia.
文章出處: D'Oliveira-Pazos L, Fossati-Cola J-M, Wolff-de-Freitas D-A, Luongo-Gardi Á, Otero M, Carrasco B: Use of platelet rich plasma as prophylactic method for skin damageafter radiotherapy: experimental study. Cirugia Plastica Ibero-Latinoamericana 2016, 42:109-114.
研究背景:
放射治療(放療)所造成的放射性皮膚炎會嚴重影響患者的生活品質，在某些情況下還會影響整形重建的癒合時間。富含血小板血漿（PRP）是一種新興療法。 PRP目前的用途包括：減緩局部發炎、促進傷口癒合、治療放療所引起的皮膚潰瘍，其用途延伸到美容整形外科領域，改善皮膚品質。
研究目的:
使用 PRP 作為放療後皮膚毛髮損傷的預防。
研究方式:
使用12 隻 Wistar 大鼠進行雙盲試驗。由其中的2隻大鼠提供捐血獲得PRP，另外10隻用於臨床和組織學分析。
結果:
在放療前沒有使用 PRP 的區域：8隻大鼠出現脫髮和7隻大鼠發生局部色素減退，其中60% 出現完全脫髮，20% 出現部分脫髮，20% 未出現脫髮。在放療前有使用 PRP 的區域：4 隻出現脫髮和 3 隻色素減退，其中無完全脫髮病例，40%出現部分脫髮，60%未出現脫髮。從組織學分析中收集的數據顯示，有使用PRP 的那些區域中，100% 出現輕至中度萎縮；另一方面，沒有使用 PRP 的區域，80% 出現中至重度萎縮，20% 出現輕至中度萎縮。
結論: PRP 可用於預防脫髮。
原文摘要:
Background and Objectives: Radiotherapy is usually associated with skin complications that affect the quality of life of patients and in some cases can also affect the timing of the reconstruction. The platelet rich plasma (PRP) is an emerging therapy; is autologous, safe and economic. Current use of PRP includes: efficacy in decreasing local inflammation, enhance wound healing, treatment of skin ulcers caused by radiotherapy and its use extends to the field of aesthetic plastic surgery improving the quality of the skin. The authors made an experimental trial to analyze the use of PRP as a prophylaxis method for skin damage after radiotherapy. We analyze the benefits of PRP as a prophylaxis method for skin damage after radiotherapy using an experimental model.
Methods: We conduct a double blind trial with rats. Twelve Wistar rats were used, 2 for obtaining the PRP and 10 for clinical and histological analysis.
Results: Data collected from the clinical analysis showed that those areas without PRP: 8 rats presented alopecia and 7 hypopigmentation. Total alopecia was present in 60%, partial alopecia in 20%, and 20% did not present alopecia. In those areas with PRP before radiotherapy: 4 presented alopecia and 3 hypopigmentation. There were no cases of total alopecia, 60% did not present alopecia and 40% presented partial alopecia. Data collected from the histological analysis showed 100% of mild-moderate atrophy in those areas with PRP. On the other hand, 80% of moderate-severe atrophy and 20% of mild-moderate atrophy was present on those areas without PRP.
Conclusions: The authors showed the benefit of PRP as a prophylaxis method for alopecia.
文章出處: D'Oliveira-Pazos L, Fossati-Cola J-M, Wolff-de-Freitas D-A, Luongo-Gardi Á, Otero M, Carrasco B: Use of platelet rich plasma as prophylactic method for skin damageafter radiotherapy: experimental study. Cirugia Plastica Ibero-Latinoamericana 2016, 42:109-114.